Of course it's harder. If it's accomplished, though, it is a dream of an energy source: more efficient, less wasteful, completely renewable, and no major environmental hazards. Being harder has never been an excuse for any innovator, so if you think it is one, stay out of the way.
The opportunity cost argument really confuses me, not just when discussing nuclear fusion but when discussing basically anything involving government funding. The idea that inefficient and/or corrupt governments give a shit about opportunity cost is laughable. The United States has had two Marine aircraft crash in the last few weeks, which makes me wonder how safe their operable aircraft even are, and 70% of their entire fleet is currently grounded due to failed budget negotiations, cuts, and the influx of parts prices. Despite this, the United States military consistently and predictably puts billions of dollars behind newer, fancier, more expensive projects - unnecessary in the grander scheme because, if they chose instead to budget money toward these existing issues, the military's capabilities would be dramatically expanded. Suppliers and contractors long ago stopped mass producing the parts necessary to make these fixes because their contracts ran out, so when a plane that was supposed to fly for 10 years is now extended to fly for 25 years, they still only get parts for 10 years. What do you do about this? If you're rational, you put together some more contracts for suppliers, you get your parts, and fix your fleet, and you try to get your budgets back in order. If you're the United States government, you come up with a fancy new bird (that sometimes flies and sometimes doesn't, parts be damned) because Lockheed Martin needs some paper.
Opportunity cost is a great word for a high school macro quiz, but if you're talking about the actual operations of the actual world, that idea gets lost in the shuffle of bureaucratic shit and special interests, two euphemisms for legal corruption. If they could be corrupt in favor of fixing our energy problems as opposed to invading [random]stan, that would be great.