Short answers:
In Europe, yes. Possibly.
In East Asia/the Pacific, no.
In Europe, I think two things key factors in 1940-41 may have changed the results of the war had they gone the other way. They are:
1) The failure of Hitler to persuade Franco to enter the war in late 1940 (unbeknownst to him, Hitler had been diplomatically knee-capped by the head of the Abwehr, Wilhelm Canaris, who had been dissuading Franco and his generals from intervening). Spanish involvement in the war would've meant the fall of Gibraltar and with it the permanent closure of the Mediterranean, Portugal likely joining the Axis, and a bunch of new bases in Africa for U-boats to cut off Britain's supply to and from India and the Middle East as it transited the South Atlantic.
2) The 5-7 week delay of Barbarossa due to the unscheduled detours to Greece and Yugoslavia in the Spring of 1941. An earlier start would've given more time to take Moscow before winter set in. And the Axis effort definitely would've been helped by the addition of a dozen or two battle-tested and motivated Spanish divisions, as well as the Afrika Korps had #1 gone the other way.
In East Asia/the Pacific, Japan was in trouble even before Pearl Harbor. The war in China had already come to a stalemate by then, and the Japanese government had even had to resort to rationing in 1940. Japan's early victories against superior enemies were somewhat impressive in early '42, but there was no way it was going to win against a country that was commissioning a new fleet carrier (plus the planes and pilots to go with it) every month by the close of 1944. If the Japanese had decisively won Coral Sea, Midway, or Guadalcanal, all it would've done is draw the war out longer - maybe another 12 or 18 months at most - and may perhaps have resulted in a conditional surrender in late '46 or early '47, but there was no way Japan was going to walk away with a win.